WHO / Andrew Quilty
COVID-19 vaccines arrive in Afghanistan via COVAX. On 24 March 2021, a nurse working at Shaidayee Hospital in Herat, Afghanistan, treats a patient with oxygen
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Oxygen

    Overview

    Oxygen is a life-saving essential medicine with no substitution. Healthcare professionals use oxygen to treat respiratory illnesses like COVID-19 and pneumonia. Oxygen is also essential for surgery and trauma. Vulnerable groups like older people, pregnant women, young infants and newborns need oxygen therapy regularly. 

    Despite being an essential medicine, oxygen is a complex product. Medicinal oxygen is produced in an industrial process applying good manufacturing practices (GMP) or is generated on-site using oxygen concentrators, which are in many legislations regulated as medical devices. Oxygen also requires a whole system to safely reach patients.

    Due to their complexity, access to medical oxygen meets many challenges on availability, quality, affordability, management, supply, human resources capacity and safety. In face of these challenges, WHO continuously develops resources and tools to overcome them.

    Impact

    Surveys in low- and middle-income countries (LMICs) have found that fewer than half of all health facilities have uninterrupted access to oxygen. It has been reported that the lack of access to reliable oxygen supplies contributes to preventable deaths, particularly in LMICs. For example, it has been estimated that up to 122 000 deaths from childhood pneumonia could be prevented annually with the strengthening of oxygen supplies. Numerous studies show that oxygen access is a global problem. For example, a recent study found that among facilities treating respiratory infections in sub-Saharan Africa, only 1 in 5 had oxygen in Mauritania and 1 in 10 in Niger. Surveys by the United States Agency for International Development found similar situations for countries in South America and South Asia. A serious concern at any time, the global medical oxygen problem has been exacerbated by the COVID-19 pandemic. 

    Despite being an essential medicine, producing oxygen that is safe for patient use is a complex process since it requires the devices and systems needed to deliver oxygen to patients, ranging from pulse oximeters to ventilators, and health workers that are trained to use such devices effectively. However daunting, the investment of time and resources required to meet oxygen supply demand is worth it. The support for the urgent scale-up of medicinal oxygen will save lives by improving care for people with COVID-19, severe pneumonia and other conditions needing oxygen therapy.

    WHO Response

    WHO is continuously updating guidance on the clinical use of oxygen for different diseases and health conditions. 

    WHO’s efforts include the development of technical specifications, the development and dissemination of guidelines on the assessment of hypoxaemia and medical oxygen use, the development of the foundations of medical oxygen systems and the provision of technical and operational support to Member States.

    The purpose of technical specifications is to increase access to quality products. It also aims to ensure the supply of oxygen in low-resource settings. These efforts aim to support Member States’ ministries of health by: 

    1. ensuring oxygen supply is readily available; and 
    2. highlighting the importance of appropriate selection, procurement, maintenance, and use of medical devices.

    When the COVID-19 pandemic erupted in 2020, the Access to COVID-19 Tools (ACT) Accelerator was created with two objectives: the rapid development of vaccines, diagnostics and therapeutics; and equitable access to these tools. Under the ACT Accelerator, the Oxygen Emergency Taskforce was launched, in partnership with WHO, to assess oxygen needs in low- and middle-income countries (LMICs), support oxygen-related funding requests, procure oxygen products, and increase access to oxygen in LMICs.

    Publications

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    Summary of WHO symposium on meeting the global needs for oxygen and respiratory care

    Global access to oxygen and options to deliver respiratory support are limited, and patient needs in low- and middle-income countries (LMICs) are unmet....

    Foundations of 
medical oxygen 
systems

    Foundations of medical oxygen systems has been complied to capture definitions, technical requirements, tools and resources related to medical oxygen systems...

    Developing key performance indicators for the medical oxygen ecosystem through Delphi consensus

    The COVID-19 pandemic has highlighted the importance of and inequities in access to life-saving medical oxygen. However, no consolidated list of Key Performance...

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