My Bibliography

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Monzel AS, Levin M, Picard M. The energetics of cellular life transitions. Life Metab. 2024 Jun;3(3). doi: 10.1093/lifemeta/load051. Epub 2023 Dec 27. PubMed PMID: 38566850; PubMed Central PMCID: PMC10984639.

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Basarrate S, Monzel AS, Smith JLM, Marsland AL, Trumpff C, Picard M. Glucocorticoid and Adrenergic Receptor Distribution Across Human Organs and Tissues: A Map for Stress Transduction. Psychosom Med. 2024 Feb-Mar 01;86(2):89-98. doi: 10.1097/PSY.0000000000001275. Epub 2024 Jan 8. PubMed PMID: 38193786; PubMed Central PMCID: PMC10922488.

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Ware SA, Kliment CR, Giordano L, Redding KM, Rumsey WL, Bates S, Zhang Y, Sciurba FC, Nouraie SM, Kaufman BA. Cell-free DNA levels associate with COPD exacerbations and mortality. Respir Res. 2024 Jan 18;25(1):42. doi: 10.1186/s12931-023-02658-1. PubMed PMID: 38238743; PubMed Central PMCID: PMC10797855.

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Kamat V, Grumbine MK, Bao K, Mokate K, Khalil G, Cook D, Clearwater B, Hirst R, Harman J, Boeck M, Fu Z, Smith LEH, Goswami M, Wubben TJ, Walker EM, Zhu J, Soleimanpour SA, Scarlett JM, Robbings BM, Hass D, Hurley JB, Sweet IR. A versatile pumpless multi-channel fluidics system for maintenance and real-time functional assessment of tissue and cells. Cell Rep Methods. 2023 Nov 20;3(11):100642. doi: 10.1016/j.crmeth.2023.100642. Epub 2023 Nov 13. PubMed PMID: 37963464; PubMed Central PMCID: PMC10694526.

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Sullivan DI, Bello FM, Silva AG, Redding KM, Giordano L, Hinchie AM, Loughridge KE, Mora AL, Königshoff M, Kaufman BA, Jurczak MJ, Alder JK. Intact mitochondrial function in the setting of telomere-induced senescence. Aging Cell. 2023 Oct;22(10):e13941. doi: 10.1111/acel.13941. Epub 2023 Sep 8. PubMed PMID: 37688329; PubMed Central PMCID: PMC10577573.

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Levi-D'Ancona E, Sidarala V, Soleimanpour SA. Complementary Approaches to Interrogate Mitophagy Flux in Pancreatic β-Cells. J Vis Exp. 2023 Sep 15;(199). doi: 10.3791/65789. PubMed PMID: 37782087; PubMed Central PMCID: PMC10597842.

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Bobba-Alves N, Sturm G, Lin J, Ware SA, Karan KR, Monzel AS, Bris C, Procaccio V, Lenaers G, Higgins-Chen A, Levine M, Horvath S, Santhanam BS, Kaufman BA, Hirano M, Epel E, Picard M. Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging. Psychoneuroendocrinology. 2023 Sep;155:106322. doi: 10.1016/j.psyneuen.2023.106322. Epub 2023 Jun 14. PubMed PMID: 37423094; PubMed Central PMCID: PMC10528419.

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Michelson J, Rausser S, Peng A, Yu T, Sturm G, Trumpff C, Kaufman BA, Rai AJ, Picard M. MitoQuicLy: A high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva. Mitochondrion. 2023 Jul;71:26-39. doi: 10.1016/j.mito.2023.05.001. Epub 2023 May 10. PubMed PMID: 37172669; PubMed Central PMCID: PMC10524316.

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Rutledge C, Enriquez A, Redding K, Lopez M, Mullett S, Gelhaus SL, Jurczak M, Goetzman E, Kaufman BA. Liraglutide Protects Against Diastolic Dysfunction and Improves Ventricular Protein Translation. Cardiovasc Drugs Ther. 2023 Jun 29;. doi: 10.1007/s10557-023-07482-9. [Epub ahead of print] PubMed PMID: 37382868; PubMed Central PMCID: PMC10788853.

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Zhang M, Feng N, Peng Z, Thapa D, Stoner MW, Manning JR, McTiernan CF, Yang X, Jurczak MJ, Guimaraes D, Rao K, Shiva S, Kaufman BA, Sack MN, Scott I. Reduced acetylation of TFAM promotes bioenergetic dysfunction in the failing heart. iScience. 2023 Jun 16;26(6):106942. doi: 10.1016/j.isci.2023.106942. eCollection 2023 Jun 16. PubMed PMID: 37305705; PubMed Central PMCID: PMC10250906.

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Rutter GA, Sidarala V, Kaufman BA, Soleimanpour SA. Mitochondrial metabolism and dynamics in pancreatic beta cell glucose sensing. Biochem J. 2023 Jun 15;480(11):773-789. doi: 10.1042/BCJ20230167. Review. PubMed PMID: 37284792.

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Rutledge CA, Lagranha C, Chiba T, Redding K, Stolz DB, Goetzman E, Sims-Lucas S, Kaufman BA. Metformin preconditioning protects against myocardial stunning and preserves protein translation in a mouse model of cardiac arrest. J Mol Cell Cardiol Plus. 2023 Jun;4. doi: 10.1016/j.jmccpl.2023.100034. Epub 2023 Apr 5. PubMed PMID: 37425219; PubMed Central PMCID: PMC10327679.

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Monzel AS, Enríquez JA, Picard M. Multifaceted mitochondria: moving mitochondrial science beyond function and dysfunction. Nat Metab. 2023 Apr;5(4):546-562. doi: 10.1038/s42255-023-00783-1. Epub 2023 Apr 26. Review. PubMed PMID: 37100996; PubMed Central PMCID: PMC10427836.

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Verma M, Francis L, Lizama BN, Callio J, Fricklas G, Wang KZQ, Kaufman BA, D'Aiuto L, Stolz DB, Watkins SC, Nimgaonkar VL, Soto-Gutierrez A, Goldstein A, Chu CT. iPSC-Derived Neurons from Patients with POLG Mutations Exhibit Decreased Mitochondrial Content and Dendrite Simplification. Am J Pathol. 2023 Feb;193(2):201-212. doi: 10.1016/j.ajpath.2022.11.002. Epub 2022 Nov 19. PubMed PMID: 36414085; PubMed Central PMCID: PMC9976192.

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Sturm G, Karan KR, Monzel AS, Santhanam B, Taivassalo T, Bris C, Ware SA, Cross M, Towheed A, Higgins-Chen A, McManus MJ, Cardenas A, Lin J, Epel ES, Rahman S, Vissing J, Grassi B, Levine M, Horvath S, Haller RG, Lenaers G, Wallace DC, St-Onge MP, Tavazoie S, Procaccio V, Kaufman BA, Seifert EL, Hirano M, Picard M. OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases. Commun Biol. 2023 Jan 12;6(1):22. doi: 10.1038/s42003-022-04303-x. PubMed PMID: 36635485; PubMed Central PMCID: PMC9837150.

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Sturm G, Monzel AS, Karan KR, Michelson J, Ware SA, Cardenas A, Lin J, Bris C, Santhanam B, Murphy MP, Levine ME, Horvath S, Belsky DW, Wang S, Procaccio V, Kaufman BA, Hirano M, Picard M. A multi-omics longitudinal aging dataset in primary human fibroblasts with mitochondrial perturbations. Sci Data. 2022 Dec 3;9(1):751. doi: 10.1038/s41597-022-01852-y. PubMed PMID: 36463290; PubMed Central PMCID: PMC9719499.

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Bobba-Alves N, Juster RP, Picard M. The energetic cost of allostasis and allostatic load. Psychoneuroendocrinology. 2022 Dec;146:105951. doi: 10.1016/j.psyneuen.2022.105951. Epub 2022 Oct 8. PubMed PMID: 36302295; PubMed Central PMCID: PMC10082134.

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Picard M, Shirihai OS. Mitochondrial signal transduction. Cell Metab. 2022 Nov 1;34(11):1620-1653. doi: 10.1016/j.cmet.2022.10.008. Review. PubMed PMID: 36323233; PubMed Central PMCID: PMC9692202.

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Carew NT, Schmidt HM, Yuan S, Galley JC, Hall R, Altmann HM, Hahn SA, Miller MP, Wood KC, Gabris B, Stapleton MC, Hartwick S, Fazzari M, Wu YL, Trebak M, Kaufman BA, McTiernan CF, Schopfer FJ, Navas P, Thibodeau PH, McNamara DM, Salama G, Straub AC. Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death. J Clin Invest. 2022 Sep 15;132(18). doi: 10.1172/JCI147120. PubMed PMID: 36106636; PubMed Central PMCID: PMC9479700.

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Trumpff C, Rausser S, Haahr R, Karan KR, Gouspillou G, Puterman E, Kirschbaum C, Picard M. Dynamic behavior of cell-free mitochondrial DNA in human saliva. Psychoneuroendocrinology. 2022 Sep;143:105852. doi: 10.1016/j.psyneuen.2022.105852. Epub 2022 Jun 30. PubMed PMID: 35834882; PubMed Central PMCID: PMC9880596.

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Tian G, Katchur SR, Jiang Y, Briand J, Schaber M, Kreatsoulas C, Schwartz B, Thrall S, Davis AM, Duvall S, Kaufman BA, Rumsey WL. Small molecule-mediated allosteric activation of the base excision repair enzyme 8-oxoguanine DNA glycosylase and its impact on mitochondrial function. Sci Rep. 2022 Aug 29;12(1):14685. doi: 10.1038/s41598-022-18878-2. PubMed PMID: 36038587; PubMed Central PMCID: PMC9424235.

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Karan KR, Trumpff C, Cross M, Engelstad KM, Marsland AL, McGuire PJ, Hirano M, Picard M. Leukocyte cytokine responses in adult patients with mitochondrial DNA defects. J Mol Med (Berl). 2022 Jun;100(6):963-971. doi: 10.1007/s00109-022-02206-2. Epub 2022 May 30. PubMed PMID: 35635577; PubMed Central PMCID: PMC9885136.

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Rutledge CA, Kaufman BA, Dezfulian C, Elmer J. Metformin protects against cardiac and renal damage in diabetic cardiac arrest patients. Resuscitation. 2022 May;174:42-46. doi: 10.1016/j.resuscitation.2022.03.017. Epub 2022 Mar 21. PubMed PMID: 35331801; PubMed Central PMCID: PMC9050929.

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Sidarala V, Zhu J, Levi-D'Ancona E, Pearson GL, Reck EC, Walker EM, Kaufman BA, Soleimanpour SA. Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis. Nat Commun. 2022 Apr 29;13(1):2340. doi: 10.1038/s41467-022-29945-7. PubMed PMID: 35487893; PubMed Central PMCID: PMC9055072.

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Nath S, Caron NS, May L, Gluscencova OB, Kolesar J, Brady L, Kaufman BA, Boulianne GL, Rodriguez AR, Tarnopolsky MA, Truant R. Functional characterization of variants of unknown significance in a spinocerebellar ataxia patient using an unsupervised machine learning pipeline. Hum Genome Var. 2022 Apr 14;9(1):10. doi: 10.1038/s41439-022-00188-8. PubMed PMID: 35422034; PubMed Central PMCID: PMC9010413.

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Dosunmu-Ogunbi A, Yuan S, Reynolds M, Giordano L, Sanker S, Sullivan M, Stolz DB, Kaufman BA, Wood KC, Zhang Y, Shiva S, Nouraie SM, Straub AC. SOD2 V16A amplifies vascular dysfunction in sickle cell patients by curtailing mitochondria complex IV activity. Blood. 2022 Mar 17;139(11):1760-1765. doi: 10.1182/blood.2021013350. PubMed PMID: 34958669; PubMed Central PMCID: PMC8931509.

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Junker A, Wang J, Gouspillou G, Ehinger JK, Elmér E, Sjövall F, Fisher-Wellman KH, Neufer PD, Molina AJA, Ferrucci L, Picard M. Human studies of mitochondrial biology demonstrate an overall lack of binary sex differences: A multivariate meta-analysis. FASEB J. 2022 Feb;36(2):e22146. doi: 10.1096/fj.202101628R. PubMed PMID: 35073429; PubMed Central PMCID: PMC9885138.

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Giordano L, Gregory AD, Pérez Verdaguer M, Ware SA, Harvey H, DeVallance E, Brzoska T, Sundd P, Zhang Y, Sciurba FC, Shapiro SD, Kaufman BA. Extracellular Release of Mitochondrial DNA: Triggered by Cigarette Smoke and Detected in COPD. Cells. 2022 Jan 22;11(3). doi: 10.3390/cells11030369. PubMed PMID: 35159179; PubMed Central PMCID: PMC8834490.

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Rausser S, Trumpff C, McGill MA, Junker A, Wang W, Ho SH, Mitchell A, Karan KR, Monk C, Segerstrom SC, Reed RG, Picard M. Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures. Elife. 2021 Oct 26;10. doi: 10.7554/eLife.70899. PubMed PMID: 34698636; PubMed Central PMCID: PMC8612706.

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Kanshana JS, Mattila PE, Ewing MC, Wood AN, Schoiswohl G, Meyer AC, Kowalski A, Rosenthal SL, Gingras S, Kaufman BA, Lu R, Weeks DE, McGarvey ST, Minster RL, Hawley NL, Kershaw EE. A murine model of the human CREBRFR457Q obesity-risk variant does not influence energy or glucose homeostasis in response to nutritional stress. PLoS One. 2021;16(9):e0251895. doi: 10.1371/journal.pone.0251895. eCollection 2021. PubMed PMID: 34520472; PubMed Central PMCID: PMC8439463.

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Picard M. Blood mitochondrial DNA copy number: What are we counting?. Mitochondrion. 2021 Sep;60:1-11. doi: 10.1016/j.mito.2021.06.010. Epub 2021 Jun 19. Review. PubMed PMID: 34157430; PubMed Central PMCID: PMC8464495.

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Trumpff C, Michelson J, Lagranha CJ, Taleon V, Karan KR, Sturm G, Lindqvist D, Fernström J, Moser D, Kaufman BA, Picard M. Stress and circulating cell-free mitochondrial DNA: A systematic review of human studies, physiological considerations, and technical recommendations. Mitochondrion. 2021 Jul;59:225-245. doi: 10.1016/j.mito.2021.04.002. Epub 2021 Apr 9. Review. PubMed PMID: 33839318; PubMed Central PMCID: PMC8418815.

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Kaufman BA, Mora AL. IRGM1, a guardian of mitochondrial DAMP-mediated autoinflammation. Nat Immunol. 2021 Mar;22(3):272-273. doi: 10.1038/s41590-021-00877-6. PubMed PMID: 33547457; PubMed Central PMCID: PMC8607984.

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Levy MA, Kerkhof J, Belmonte FR, Kaufman BA, Bhai P, Brady L, Bursztyn LLCD, Tarnopolsky M, Rupar T, Sadikovic B. Validation and clinical performance of a combined nuclear-mitochondrial next-generation sequencing and copy number variant analysis panel in a Canadian population. Am J Med Genet A. 2021 Feb;185(2):486-499. doi: 10.1002/ajmg.a.61998. Epub 2020 Dec 10. PubMed PMID: 33300680.

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Rutledge CA, Chiba T, Redding K, Dezfulian C, Sims-Lucas S, Kaufman BA. A novel ultrasound-guided mouse model of sudden cardiac arrest. PLoS One. 2020;15(12):e0237292. doi: 10.1371/journal.pone.0237292. eCollection 2020. PubMed PMID: 33275630; PubMed Central PMCID: PMC7717537.

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Ware SA, Desai N, Lopez M, Leach D, Zhang Y, Giordano L, Nouraie M, Picard M, Kaufman BA. An automated, high-throughput methodology optimized for quantitative cell-free mitochondrial and nuclear DNA isolation from plasma. J Biol Chem. 2020 Nov 13;295(46):15677-15691. doi: 10.1074/jbc.RA120.015237. Epub 2020 Sep 8. PubMed PMID: 32900851; PubMed Central PMCID: PMC7667980.

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Edmunds LR, Xie B, Mills AM, Huckestein BR, Undamatla R, Murali A, Pangburn MM, Martin J, Sipula I, Kaufman BA, Scott I, Jurczak MJ. Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance. Mol Metab. 2020 Nov;41:101051. doi: 10.1016/j.molmet.2020.101051. Epub 2020 Jul 10. PubMed PMID: 32653576; PubMed Central PMCID: PMC7399260.

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Cole LK, Mejia EM, Sparagna GC, Vandel M, Xiang B, Han X, Dedousis N, Kaufman BA, Dolinsky VW, Hatch GM. Cardiolipin deficiency elevates susceptibility to a lipotoxic hypertrophic cardiomyopathy. J Mol Cell Cardiol. 2020 Jul;144:24-34. doi: 10.1016/j.yjmcc.2020.05.001. Epub 2020 May 11. PubMed PMID: 32418915.

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Karan KR, Trumpff C, McGill MA, Thomas JE, Sturm G, Lauriola V, Sloan RP, Rohleder N, Kaufman BA, Marsland AL, Picard M. Mitochondrial respiratory capacity modulates LPS-induced inflammatory signatures in human blood. Brain Behav Immun Health. 2020 May;5. doi: 10.1016/j.bbih.2020.100080. Epub 2020 May 6. PubMed PMID: 33073254; PubMed Central PMCID: PMC7561023.

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Rutledge C, Cater G, McMahon B, Guo L, Nouraie SM, Wu Y, Villanueva F, Kaufman BA. Commercial 4-dimensional echocardiography for murine heart volumetric evaluation after myocardial infarction. Cardiovasc Ultrasound. 2020 Mar 12;18(1):9. doi: 10.1186/s12947-020-00191-5. PubMed PMID: 32164714; PubMed Central PMCID: PMC7068892.

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Kolesar JE, Kaufman BA. Using Two-Dimensional Intact Mitochondrial DNA (mtDNA) Agarose Gel Electrophoresis (2D-IMAGE) to Detect Changes in Topology Associated with Mitochondrial Replication, Transcription, and Damage. Methods Mol Biol. 2020;2119:25-42. doi: 10.1007/978-1-0716-0323-9_3. PubMed PMID: 31989512.

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Naeem MM, Maheshan R, Costford SR, Wahedi A, Trajkovski M, Plavec J, Yatsunyk LA, Ciesielski GL, Kaufman BA, Sondheimer N. G-quadruplex-mediated reduction of a pathogenic mitochondrial heteroplasmy. Hum Mol Genet. 2019 Oct 1;28(19):3163-3174. doi: 10.1093/hmg/ddz153. PubMed PMID: 31261379.

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Chung KW, Dhillon P, Huang S, Sheng X, Shrestha R, Qiu C, Kaufman BA, Park J, Pei L, Baur J, Palmer M, Susztak K. Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis. Cell Metab. 2019 Oct 1;30(4):784-799.e5. doi: 10.1016/j.cmet.2019.08.003. Epub 2019 Aug 29. PubMed PMID: 31474566; PubMed Central PMCID: PMC7054893.

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Trumpff C, Marsland AL, Sloan RP, Kaufman BA, Picard M. Predictors of ccf-mtDNA reactivity to acute psychological stress identified using machine learning classifiers: A proof-of-concept. Psychoneuroendocrinology. 2019 Sep;107:82-92. doi: 10.1016/j.psyneuen.2019.05.001. Epub 2019 May 7. PubMed PMID: 31112904; PubMed Central PMCID: PMC6637411.

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Trumpff C, Marsland AL, Basualto-Alarcón C, Martin JL, Carroll JE, Sturm G, Vincent AE, Mosharov EV, Gu Z, Kaufman BA, Picard M. Acute psychological stress increases serum circulating cell-free mitochondrial DNA. Psychoneuroendocrinology. 2019 Aug;106:268-276. doi: 10.1016/j.psyneuen.2019.03.026. Epub 2019 Mar 28. PubMed PMID: 31029929; PubMed Central PMCID: PMC6589121.

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Han LKM, Verhoeven JE, Tyrka AR, Penninx BWJH, Wolkowitz OM, Månsson KNT, Lindqvist D, Boks MP, Révész D, Mellon SH, Picard M. Accelerating research on biological aging and mental health: Current challenges and future directions. Psychoneuroendocrinology. 2019 Aug;106:293-311. doi: 10.1016/j.psyneuen.2019.04.004. Epub 2019 Apr 5. Review. PubMed PMID: 31154264; PubMed Central PMCID: PMC6589133.

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Picard M, Trumpff C, Burelle Y. Mitochondrial Psychobiology: Foundations and Applications. Curr Opin Behav Sci. 2019 Aug;28:142-151. doi: 10.1016/j.cobeha.2019.04.015. Epub 2019 Jun 14. PubMed PMID: 32637466; PubMed Central PMCID: PMC7339630.

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Bueno M, Zank D, Buendia-Roldán I, Fiedler K, Mays BG, Alvarez D, Sembrat J, Kimball B, Bullock JK, Martin JL, Nouraie M, Kaufman BA, Rojas M, Pardo A, Selman M, Mora AL. PINK1 attenuates mtDNA release in alveolar epithelial cells and TLR9 mediated profibrotic responses. PLoS One. 2019;14(6):e0218003. doi: 10.1371/journal.pone.0218003. eCollection 2019. PubMed PMID: 31170232; PubMed Central PMCID: PMC6553779.

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Kaufman BA, Picard M, Sondheimer N. Mitochondrial DNA, nuclear context, and the risk for carcinogenesis. Environ Mol Mutagen. 2019 Jun;60(5):455-462. doi: 10.1002/em.22169. Epub 2018 Jan 14. Review. PubMed PMID: 29332303; PubMed Central PMCID: PMC6045969.

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Patil P, Falabella M, Saeed A, Lee D, Kaufman B, Shiva S, Croix CS, Van Houten B, Niedernhofer LJ, Robbins PD, Lee J, Gwendolyn S, Vo NV. Oxidative stress-induced senescence markedly increases disc cell bioenergetics. Mech Ageing Dev. 2019 Jun;180:97-106. doi: 10.1016/j.mad.2019.04.006. Epub 2019 Apr 17. PubMed PMID: 31002926.