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UNCW - Chemistry
DrugDISCOvery at UNCW - MARBIONC
Located in Wilmington, North Carolina, MARBIONC is a state of the art biotechnology center equipped with research laboratories and analytical instrumentation.
At MARBIONC the Drug DISCOvery team focuses on utilizing advanced analytical technologies to discover new chemical structures that could lead to advances in the medical field.
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Learn More About UNCW Chemistry & Biochemistry
Check out our Department's Introductory Video with DISCO's Holt Gordon and Brittany Denchfield!
DISCOvery Team News - Fresh Off the Press!
Pharmaceutical Chemistry Ph.D.
FIrst cohort starting Fall of 2023. Congratulations to our trail blazers - Caitlyn, Sarah, and Jared!
Academic and Industry Engagement
Congratulations to DISCOvery team members for participating in visits to Alcami in the Spring of 2022 amd 2023
ASP 2023
The UNCW DISCO group had a great showing this year with six student presenters incuding an oral presentation from Sandra Bennett!
Ready to Present Student Research!
DISCO team member prepare for 2022 Spring/Summer Poster Presentations locally and beyond.
All the best team!
Congratulations to DISCOvery Team Members for
These Most Recent Publications!
These Most Recent Publications!
A Review of the Popular Uses, Anatomical, Chemical, and Biological Aspects of Kalanchoe (Crassulaceae): A Genus of Plants Known as “Miracle Leaf” Molecules https://doi.org/10.3390/molecules28145574 (RTW, WKS and Evelyn Assis de Andrade )
Design and Discovery of Efficient Water-Soluble Ligands for Hindered Suzuki-Miyaura Coupling Reactions with Low Catalyst Load https://doi.org/10.1021/acs.orglett.3c01663 (RTW and Emily B. Crull)
Unmasking the True Identity of Rapamycin’s Minor Conformer https://doi.org/10.1021/acs.jnatprod.3c00421 (RTW and Emily B. Crull)
Cannabicitran: Its unexpected racemic nature and potential origins https://doi.org/10.1002/chir.23571 (RTW, Jared S. Wood and W. Holt Gordon)
Anomalous 1H NMR chemical shift behavior of substituted benzoic acid esters https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/mrc.5326 (RTW and Jeffrey G. Raab)
DELTA50: A Highly Accurate Database of Experimental 1H and 13C NMR Chemical Shifts Applied to DFT Benchmarking https://www.mdpi.com/1420-3049/28/6/2449 (RTW and Jared S. Wood)
Modulation of in Vitro SARS-CoV-2 Infection by Stephania tetrandra and Its Alkaloid Constituents https://pubs.acs.org/doi/full/10.1021/acs.jnatprod.3c00159 (WKS and Sarah Barr)
J-modulated 19F- and 1H-detected dual-optimized inverted 1JCC 1,n-ADEQUATE: A universal ADEQUATE experiment https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/mrc.5324 (RTW)
Origin and remedy for HSQC artifacts in proton-detected INADEQUATE spectra
https://pubs.rsc.org/en/content/articlelanding/2023/cp/d3cp00142c/unauth (RTW)
Quantitative nuclear magnetic resonance of chloride by an accurate internal standard approach
https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/mrc.5316 (RTW and Jared S. Wood)
Meet the DrugDISCOvery Team Leaders
williamsonr@uncw.edu(910) 962-2397
strangmanw@uncw.edu(910) 962-2393
Remington Poulin
Faculty Member - Research Assistant Professor | Department of Chemistry & Biochemistry | UNC - Wilmington
poulinr@uncw.edu(910) 962-4425