Authors
Sander Greenland, James M Robins
Publication date
1986/9/1
Journal
International journal of epidemiology
Volume
15
Issue
3
Pages
413-419
Publisher
Oxford University Press
Description
Non-identifiability of parameters is a well-recognized problem in classical statistics, and Bayesian statisticians have long recognized the importance of exchangeability assumptions in making statistical Inferences. A seemingly unrelated problem in epidemiology is that of confounding: bias in estimation of the effects of an exposure on disease risk, due to inherent differences in risk between exposed and unexposed individuals. Using a simple deterministic model for exposure effects, a logical connection is drawn between the concepts of identifiability, exchangeability, and confounding. This connection allows one to view the problem of confounding as arising from problems of identifiability, and reveals the exchangeability assumptions that are implicit in confounder control methods. It also provides further justification for confounder definitions based on comparability of exposure groups, as opposed to …
Total citations
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Scholar articles
S Greenland, JM Robins - International journal of epidemiology, 1986