Anatomic and clinical pathology services and infrastructure in Zambia

Am J Clin Pathol. 2024 Jan 4;161(1):89-96. doi: 10.1093/ajcp/aqad113.

Abstract

Objectives: Pathology services are limited across most of sub-Saharan Africa. We sought to ascertain the availability of anatomic and clinical pathology services and diagnostic resources in Zambia.

Methods: Two individual surveys-one for anatomic pathology and one for clinical pathology/laboratory medicine-were developed by subject matter experts. These surveys were administered to individuals involved in pathology and laboratory medicine diagnostic services at hospitals and laboratories across Zambia from May to October 2022 using the American Society for Clinical Pathology email listserv.

Results: A total of 20 responses were received from 17 unique laboratories-8 sites provide anatomic pathology (AP) services, 12 provide clinical pathology (CP) services, and 3 perform both AP and CP services. Anatomic pathology services are variable and generally limited to a few of the responding laboratories, as only 1 laboratory performs immunohistochemical staining on surgical pathology specimens, and only 2 perform general histochemical stains. Conversely, certain microbiology testing (eg, for HIV) is more widely available.

Conclusions: This study of 17 unique laboratories represents the most complete analysis of pathology capabilities in Zambia. Despite initiatives to improve pathology services, both personnel and infrastructure challenges remain. Given a population of approximately 20 million, expansion of anatomic pathology in Zambia must be prioritized.

Keywords: Africa; Zambia; anatomic pathology; clinical pathology; global health; international pathology; laboratory infrastructure.

MeSH terms

  • Clinical Laboratory Services*
  • HIV Infections*
  • Hospitals
  • Humans
  • Laboratories
  • Pathology, Clinical*
  • Zambia