Genetic Determinants of IL-6 Levels and Risk of ESKD

Kidney360. 2023 Feb 1;4(2):241-244. doi: 10.34067/KID.0003332022. Epub 2022 Dec 14.

Authors

Lee Wheless^{1

2}, Mindy M Pike^{1

2}, Hua-Chang Chen^{1

2}, Zhihong Yu^{1

2}, Ran Tao^{1

2}, Alexander Bick², Cecilia P Chung^{1

2}, Cassianne Robinson-Cohen^{1

2}, Adriana Hung^{1

2}

Affiliations

¹ Vanderbilt University Medical Center, Nashville, Tennessee.
² Tennessee Valley Health System VA Medical Center, Nashville, Tennessee.

Abstract

Genetically predicted IL-6 levels are associated with risk of ESKD.
Therapeutic modulation of IL-6 could potentially reduce the risk of ESKD.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Humans
Interleukin-6*
Kidney Failure, Chronic*
Risk Factors

Substances

Interleukin-6

Grants and funding