Non-contrast power Doppler imaging with multidimensional clutter filtering for assessment of trans-arterial chemoembolization for hepatic malignancy

Kathryn Ozgun; Jaime Tierney Stanton; Jennifer Baker; Anthony Borgmann; Daniel Brown; Brett Byram

doi:10.1117/12.2582109

15 February 2021 Non-contrast power Doppler imaging with multidimensional clutter filtering for assessment of trans-arterial chemoembolization for hepatic malignancy

Kathryn Ozgun, Jaime Tierney Stanton, Jennifer Baker, Anthony Borgmann, Daniel Brown, Brett Byram

Author Affiliations +

Proceedings Volume 11602, Medical Imaging 2021: Ultrasonic Imaging and Tomography; 116020N (2021) https://doi.org/10.1117/12.2582109
Event: SPIE Medical Imaging, 2021, Online Only

Abstract

Immediate postoperative assessment of trans-arterial chemoembolization (TACE) using gold standard modalities, MRI and CT, is unreliable due to confounding interactions with lipiodol and post-embolization inflammatory changes. We previously demonstrated that recent advancements in power Doppler ultrasound processing enables changes in slow blood flow to be detected immediately following TACE. Recently, we have developed a filtering method that employs a higherorder singular value decomposition (HOSVD) applied to aperture data to mitigate thermal noise and acoustic clutter. Here, we investigate HOSVD as a tool to improve non-contrast ultrasound evaluation of TACE. Preliminary feasibility is demonstrated in a small pilot study. Treatment-induced changes in perfusion are visualized most readily using the HOSVD filter in comparison to conventional filtering methods. The HOSVD filter produced the greatest change in contrast between pre-TACE and post-TACE power Doppler images.

Conference Presentation

Citation Download Citation

Kathryn Ozgun, Jaime Tierney Stanton, Jennifer Baker, Anthony Borgmann, Daniel Brown, and Brett Byram "Non-contrast power Doppler imaging with multidimensional clutter filtering for assessment of trans-arterial chemoembolization for hepatic malignancy", Proc. SPIE 11602, Medical Imaging 2021: Ultrasonic Imaging and Tomography, 116020N (15 February 2021); https://doi.org/10.1117/12.2582109

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